Rui-Hong Du Selected Research

Secretory Immunoglobulin A (SIgA)

1/2022	Secretory Cells Are the Primary Source of pIgR in Small Airways.
1/2021	Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD.
1/2018	Bacterial-derived Neutrophilic Inflammation Drives Lung Remodeling in a Mouse Model of Chronic Obstructive Pulmonary Disease.
1/2017	Secretory IgA Deficiency in Individual Small Airways Is Associated with Persistent Inflammation and Remodeling.
4/2016	Airway bacteria drive a progressive COPD-like phenotype in mice with polymeric immunoglobulin receptor deficiency.
12/2015	Secretory IgA from submucosal glands does not compensate for its airway surface deficiency in chronic obstructive pulmonary disease.

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Rui-Hong Du Research Topics

Disease

7	Chronic Obstructive Pulmonary Disease (COPD) 01/2022 - 12/2015
4	Inflammation (Inflammations) 01/2018 - 02/2011
3	Emphysema 01/2021 - 04/2016
2	Disease Progression 01/2022 - 04/2016
2	Airway Remodeling 01/2018 - 04/2016
1	Hypertrophy 12/2021
1	Tertiary Lymphoid Structures 01/2021
1	Pneumonia (Pneumonitis) 04/2016
1	Pulmonary Arterial Hypertension 02/2011
1	Pulmonary Hypertension 02/2011
1	Hypotension (Low Blood Pressure) 02/2011

Drug/Important Bio-Agent (IBA)

6	Secretory Immunoglobulin A (SIgA)IBA 01/2022 - 12/2015
3	Polymeric Immunoglobulin Receptors (Polymeric Immunoglobulin Receptor)IBA 01/2022 - 04/2016
2	Immunoglobulin A (IgA)IBA 01/2022 - 12/2015
2	CollagenIBA 12/2021 - 11/2021
2	AntibodiesIBA 01/2018 - 12/2015
1	Peptide Hydrolases (Proteases)FDA Link 01/2022
1	Proteins (Proteins, Gene)FDA Link 01/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2018
1	Leukocyte Elastase (Neutrophil Elastase)IBA 04/2016
1	RoflumilastIBA 04/2016
1	Type 4 Cyclic Nucleotide PhosphodiesterasesIBA 04/2016
1	MucinsIBA 12/2015
1	Phenobarbital (Luminal)FDA Link 12/2015
1	anti-IgAIBA 12/2015
1	Endothelin Receptor AntagonistsIBA 02/2011
1	Sildenafil Citrate (Viagra)FDA Link 02/2011
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2011
1	Oxidants (Oxidizing Agents)IBA 02/2011
1	sapropterin (tetrahydrobiopterin)FDA Link 02/2011